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. 2023 Jun 21;15(7):3612–3626. doi: 10.21037/jtd-23-18

Table 2. Univariable and multivariable logistic regression analysis of nodal upstaging.

Variables Univariable analysis Multivariable analysis
OR P value 95% CI OR P value 95% CI
Age 1.036 0.045 1.001, 1.073
Preoperative CEA level (>3.4 μg/L) 4.460 <0.001 2.445, 8.137 2.931 0.001 1.511, 5.688
Tumor location 0.057
   LUL
   LLL 0.976 0.953 0.440, 2.166
   RUL 0.318 0.007 0.138, 0.735
   RML 0.524 0.284 0.161, 1.707
   RLL 0.578 0.225 0.239, 1.400
Imaging tumor size (>18.3 mm) 5.216 <0.001 2.530, 10.755 3.482 0.002 1.609, 7.535
Pleural indentation sign (presence) 1.948 0.026 1.082, 3.507
Lobulation sign (presence) 3.048 <0.001 1.684, 5.516
Spiculation sign (presence) 2.746 0.001 1.492, 5.055
CTR (>0.788) 11.726 <0.001 4.864, 28.270 8.791 <0.001 3.570, 21.651

OR, odds ratio; CI, confidence interval; CEA, carcinoembryonic antigen; LUL, left upper lobe; LLL, left lower lobe; RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe; CTR, consolidation tumor ratio.