TME
|
tumor microenvironment |
ECM
|
extracellular matrix |
CAFs
|
cancer-associated fibroblasts |
TAMs
|
tumor-associated macrophages |
HA
|
hyaluronic acid |
MMPs
|
matrix Metalloproteinases |
HSPGs
|
heparan sulfate proteoglycans |
TGF-β
|
transforming growth factor beta |
CXCL12/10
|
C-X-C motif chemokine ligand 12/10 |
CXCR4/3
|
C-X-C motif chemokine receptor 4/3 |
CCR9
|
C-C motif chemokine receptors 9 |
CCL21/25
|
C-C motif chemokine ligand 21/25 |
MCP-1
|
monocyte chemoattractant protein-1 |
CSF-1
|
colony stimulating factor-1 |
IL-6
|
interleukin-6 |
PGE2
|
prostaglandin E2 |
α-SMA
|
α-smooth muscle actin |
FGF-2
|
fibroblast growth factor-2 |
PDGF
|
platelet-derived growth factor |
EGF
|
epidermal growth factor |
LOX
|
lysyl oxidase |
LOXL
|
LOX-like protein |
IGF
|
insulin-like growth factor |
HAPLN1
|
hyaluronan and proteoglycan-linked protein 1; |
HMM-HA
|
High molecular weight HA |
LMM-HA
|
low-molecular-mass HA |
PLODs
|
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenases |
TG2
|
tissue transglutaminase 2 |
ADAMs
|
disintegrin and metalloproteinases |
IGFBP-3
|
insulin-like growth factor-binding protein 3 |
VEGF-A
|
vascular endothelial growth factor-A |
TIMP
|
tissue inhibitor of metalloproteinases |
GF
|
growth factors |
MT1-MMP
|
membrane type-1 matrix metalloproteinase |
AP-1
|
activator protein-1 |
JAK2
|
Janus kinase 2 |
PCA
|
prostate cancer |
FAK
|
focal adhesion kinase |
u-PA
|
urokinase-type plasminogen activator |
GBM
|
glioblastoma multiforme |
SP-1
|
Specificity protein-1 |
Col X
|
collagen X |
Nrf2
|
nuclear factor-erythroid 2related factor 2 |
ECG
|
Epicatechin-3-gallate |
EGCG
|
Epigalloccatechin-3-gallate |
GCAFs
|
gastric cancer-associated fibroblasts |
PAI-1
|
plasminogen activator inhibitor-1 |
EMMPRIN
|
extracellular matrix metalloproteinase inducer |
TLR4
|
toll-like receptor 4 |
CDK6
|
cyclin-dependent kinase 6 |
SFDA
|
State Food and Drug Administration of China |
PD-L1
|
programmed death ligand-1 |
PD-1
|
programmed death-1 |
TGF-βR
|
TGF-β receptor |
EDB
|
extra domain B |
DDR1
|
discoid domain receptor 1 |