| References | Risk of bias domains (a) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Key Criteria | Other Criterion | Tier (b) | |||||||
| Randomization | Exposure characterization | Outcome assessment | Allocation concealment | Blinding | Attrition | Selective reporting | Other threats to internal validity | ||
| Bischoff‐Ferrari et al. 2020 | ++ | + | ++ | ++ | ++ | + | ++ | + | 1 |
| Burt et al. 2019 | ++ | + | ++ | ++ | + | ++ | ++ | + | 1 |
| Flicker et al. 2005 | ++ | −− | + | ++ | + | −− | ++ | + | 2 |
| Grant et al. 2005 | ++ | – | + | ++ | + | −− | ++ | + | 2 |
| Hin et al. 2016 | ++ | + | −− | ++ | – | ++ | ++ | + | 2 |
| Macdonald et al. 2013 | ++ | ++ | + | ++ | + | – | ++ | ++ | 1 |
| Peacock et al. 2020 | ++ | + | + | NR | + | – | ++ | + | 1 |
| Prince et al. 2008 | ++ | + | NR | ++ | + | + | ++ | ++ | 2 |
Expert judgement was translated into a rating scale for each question to be answered as follows: (++): definitely low RoB; (+): probably low RoB; (NR): not reported; (−): probably high RoB; (−−): definitively high RoB.
The individual rating for each question was combined by an algorithm and translated to an overall tier of reliability for each individual study (RoB tier 1: low RoB; RoB tier 2: moderate RoB; RoB tier 3: high RoB).