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. 2023 Aug 8;21(8):e08145. doi: 10.2903/j.efsa.2023.8145
References Risk of bias domains (a)
Key Criteria Other Criterion Tier (b)
Randomization Exposure characterization Outcome assessment Allocation concealment Blinding Attrition Selective reporting Other threats to internal validity
Appel et al. 2021 −− + ++ + + ++ + 2
Bischoff‐Ferrari et al. 2022 ++ ++ ++ ++ + ++ + 2
Burt et al. 2019 ++ + ++ ++ + ++ ++ + 1
Flicker et al. 2005 ++ −− + ++ + −− ++ + 2
Grant et al. 2005 ++ + ++ + −− ++ + 2
Hin et al. 2016 ++ + −− ++ ++ ++ + 2
LeBoff et al. 2020a ++ NR + NR ++ + 2
Prince et al. 2008 ++ + NR ++ + + ++ ++ 2
Smith et al. 2017 ++ ++ −− ++ + NR ++ 2
Uusi‐Rasi et al. 2015 ++ + ++ ++ ++ + ++ ++ 1
Wood et al. 2014 ++ ++ −− ++ + + ++ ++ 2
(a)

Expert judgement was translated into a rating scale for each question to be answered as follows: (++): definitely low RoB; (+): probably low RoB; (NR): not reported; (−): probably high RoB; (−−): definitively high RoB.

(b)

The individual rating for each question was combined by an algorithm and translated to an overall tier of reliability for each individual study (RoB tier 1: low RoB; RoB tier 2: moderate RoB; RoB tier 3: high RoB).