Table 1.
LC-MS/MS optimized parameters for the determination of decitabine, venetoclax and IS.
| Drug | Retention time (min) | Ion mode | Precursor (m/z) | Quantification trace (m/z) | Qualification trace (m/z) | Cone Voltage (V) | Collision energy (CE, eV) |
|---|---|---|---|---|---|---|---|
| DCB | 0.98 | +ve | 229.03 | 113.03 | 98.94 | 8 | 10/22 |
| VTX | 2.44 | +ve | 868.28 | 177.05 | 321.13 | 50 | 38/44 |
| ENF (IS) | 1.48 | +ve | 540.10 | 359.10 | 116.00 | 54 | 46/44 |