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. 2023 Jul 6;31(9):101697. doi: 10.1016/j.jsps.2023.101697

Table 3.

Stabilizers used for preparation of the nanoformulation.

NO Code D:P (mg) Stabilizer (10 mL) Stabilizer (%) Size (nm) PDI Z.P(mv) E. E (%)
01 PTX 01 1:10 PVA 1:0 347 ± 10.3 0.6 ± 0.01 −8.1 ± 1.8 55
02 PTX 05 1:10 Pluronic F-127 1:0 190 ± 13.2 0.2 ± 0.03 −8.1 ± 1.8 71
03 PTX 21 1:10 Poloxamer 407 1:0 249 ± 9.7 0.19 ± 0.01 −5.6 ± 0.21 83
04 PTX 124 1:10 Tween 80 1:0 261 ± 12.2 0. ± 0.04 −7.39 ± 0.1 41
05 PTX 126 1:10 Span 20 1:0 160 ± 11.9 0.9 ± 0.2 0.6 ± 1.1 25
06 PTX 131 1:10 SDS 1:0 482 ± 7.1 0.9 ± 0.01 −51.6 ± 0.1 24
07 PTX 142 1:10 SLS 1:0 203 ± 7.3 0.4 ± 0.06 −40.8 ± 1.4 56
08 PTX 66 1:10 PVAa + SLSb 1:0.05 279 ± 13.1 0.8 ± 0.04 −4.16 ± 0.11 68
09 PTX 88 1:10 Pluronic F-127a + SLSb 1:0.05 371 ± 22.61 0.7 ± 0.02 −29.77 ± 0.2 76
10 PTX 104 1:10 Poloxamer 407a + SLSb 1:0.05 199 ± 21.80 0.4 ± 0.01 −26.85 ± 0.03 77
11 PTX 120 1:10 Tween 80a + SLSb 1:0.05 198 ± 14.6 0.4 ± 0.23 −43.2 ± 1.01 41
12 PTX 133 1:10 SDSa + SLSb 1:0.05 333 ± 15.5 0.5 ± 0.05 −50.1 ± 0.21 35
13 PTX 137 1:10 Span 20a + SLSb 1:0.05 391 ± 9.7 0.9 ± 0.06 −60.2 ± 0.09 66
a

5 mL, b 5 mL, D: Paclitaxel, P: PLGA.