Table 3.
NO | Code | D:P (mg) | Stabilizer (10 mL) | Stabilizer (%) | Size (nm) | PDI | Z.P(mv) | E. E (%) |
---|---|---|---|---|---|---|---|---|
01 | PTX 01 | 1:10 | PVA | 1:0 | 347 ± 10.3 | 0.6 ± 0.01 | −8.1 ± 1.8 | 55 |
02 | PTX 05 | 1:10 | Pluronic F-127 | 1:0 | 190 ± 13.2 | 0.2 ± 0.03 | −8.1 ± 1.8 | 71 |
03 | PTX 21 | 1:10 | Poloxamer 407 | 1:0 | 249 ± 9.7 | 0.19 ± 0.01 | −5.6 ± 0.21 | 83 |
04 | PTX 124 | 1:10 | Tween 80 | 1:0 | 261 ± 12.2 | 0. ± 0.04 | −7.39 ± 0.1 | 41 |
05 | PTX 126 | 1:10 | Span 20 | 1:0 | 160 ± 11.9 | 0.9 ± 0.2 | 0.6 ± 1.1 | 25 |
06 | PTX 131 | 1:10 | SDS | 1:0 | 482 ± 7.1 | 0.9 ± 0.01 | −51.6 ± 0.1 | 24 |
07 | PTX 142 | 1:10 | SLS | 1:0 | 203 ± 7.3 | 0.4 ± 0.06 | −40.8 ± 1.4 | 56 |
08 | PTX 66 | 1:10 | PVAa + SLSb | 1:0.05 | 279 ± 13.1 | 0.8 ± 0.04 | −4.16 ± 0.11 | 68 |
09 | PTX 88 | 1:10 | Pluronic F-127a + SLSb | 1:0.05 | 371 ± 22.61 | 0.7 ± 0.02 | −29.77 ± 0.2 | 76 |
10 | PTX 104 | 1:10 | Poloxamer 407a + SLSb | 1:0.05 | 199 ± 21.80 | 0.4 ± 0.01 | −26.85 ± 0.03 | 77 |
11 | PTX 120 | 1:10 | Tween 80a + SLSb | 1:0.05 | 198 ± 14.6 | 0.4 ± 0.23 | −43.2 ± 1.01 | 41 |
12 | PTX 133 | 1:10 | SDSa + SLSb | 1:0.05 | 333 ± 15.5 | 0.5 ± 0.05 | −50.1 ± 0.21 | 35 |
13 | PTX 137 | 1:10 | Span 20a + SLSb | 1:0.05 | 391 ± 9.7 | 0.9 ± 0.06 | −60.2 ± 0.09 | 66 |
5 mL, b 5 mL, D: Paclitaxel, P: PLGA.