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. 2023 Jul 6;31(9):101697. doi: 10.1016/j.jsps.2023.101697

Table 4.

Formulation of paclitaxel with PLGA, 0.05% SLS and PVA.

NO Code D:P (mg) Size (nm) PDI Z.P (mv) Amount Encapsulate (mg/mL) (%) E.E (%) Drug Loading
PVA (0.5%)
01 PTX 67 1:10 289 ± 0.12 0.3 ± 0.01 −4 ± 0.5 0.81 81% 8.1
02 PTX 68 2:10 378 ± 22.11 0.9 ± 0.04 −7 ± 0.3 1.1 55% 11
03 PTX 69 3:10 528 ± 12.3 1.0 ± 0.05 −3 ± 0.4 2.94 98% 29.4
04 PTX 70 4:10 620 ± 11.1 0.3 ± 0.01 −7 ± 0.5 3.88 97% 38.8
PVA (1%)
05 PTX 72 1:10 244 ± 0.19 0.3 ± 0.02 −3 ± 0.2 0.78 78% 7.8
06 PTX 73 2:10 349 ± 12.08 0.5 ± 0.03 −4 ± 0.6 1.92 96% 19.2
07 PTX 74 3:10 327 ± 23.2 0.7 ± 0.03 −2.20 ± 0.3 2.52 84% 25.2
08 PTX 75 4:10 365 ± 10.91 0.6 ± 0.04 −5.11 ± 0.4 3.80 95% 38
PVA (1.5%)
09 PTX 76 1:10 408 ± 26.13 0.2 ± 0.02 −3.25 ± 0.2 0.94 94% 9.4
10 PTX 77 2:10 496 ± 7.09 0.3 ± 0.01 −3.71 ± 0.1 0.19 95% 1.9
11 PTX 78 3:10 1042 ± 11.1 1.0 ± 0.04 −7.75 ± 0.6 2.91 97% 29.1
12 PTX 79 4:10 1040 ± 0.19 1.0 ± 0.05 −4.31 ± 0.5 3.84 96% 38.4
PVA (2%)
13 PTX 80 1:10 315 ± 18.45 0.3 ± 0.01 −2.23 ± 0.3 0.94 94% 9.4
14 PTX 81 2:10 402 ± 23.66 0.6 ± 0.02 −1.53 ± 0.2 1.84 92% 18.4
15 PTX 82 3:10 529 ± 34.24 0.9 ± 0.01 −1.15 ± 0.1 2.64 88% 26.4
16 PTX 83 4:10 601 ± 43.21 0.5 ± 0.03 −1.1 ± 0.1 3.36 84% 33.6

D: Paclitaxel, P: PLGA.