Table 5.

Formulation of paclitaxel with PLGA, 0.05% SLS and Pluronic F-127.

NO	Code	D:P (mg)	Size (nm)	PDI	Z.P (mv)	Amount Encapsulate (mg/mL)	(%) E.E	(%) Drug Loading
Pluronic F-127 (0.5%)
01	PTX 84	1:10	190 ± 12.42	0.13 ± 0.02	−30.2 ± 1.1	0.95	95	9.5
02	PTX 85	2:10	265 ± 3.38	0.5 ± 0.03	−30.9 ± 0.8	1.1	55	11
03	PTX 86	3:10	287 ± 13.51	0.2 ± 0.01	−35.8 ± 1.2	2.43	81	24.3
04	PTX 87	4:10	373 ± 14.47	0.9 ± 0.08	−38.5 ± 1.9	2.52	63	25.2
Pluronic F-127 (1 %)
05	PTX 88	1:10	371 ± 22.61	0.7 ± 0.02	−29.77 ± 0.2	0.66	66	6.6
06	PTX 89	2:10	380 ± 38.97	0.6 ± 0.04	−24.2 ± 0.18	1.22	61	12.2
07	PTX 90	3:10	453 ± 48.10	0.6 ± 0.01	−30.8 ± 0.1	1.26	42	12.6
08	PTX 91	4:10	363 ± 44.0	0.4 ± 0.04	−34.7 ± 0.2	1.52	38	15.2
Pluronic F-127 (1.5 %)
09	PTX 92	1:10	261 ± 11.8	0.4 ± 0.03	−24.05 ± 0.9	0.47	47	4.7
10	PTX 93	2:10	385 ± 33.4	1.0 ± 0.04	−30.59 ± 0.11	1.96	98	19.6
11	PTX 94	3:10	458 ± 18.5	0.5 ± 0.04	−31 ± 0.25	1.35	45	13.5
12	PTX 95	4:10	431 ± 23.9	0.19 ± 0.01	–33.62 ± 1.7	2.0	50	20
Pluronic F-127 (2 %)
13	PTX 96	1:10	226 ± 34.37	0.5 ± 0.02	−28.28 ± 1.2	0.44	44	4.4
14	PTX 97	2:10	243 ± 10.04	0.1 ± 0.02	−29.89 ± 0.9	0.38	19	3.8
15	PTX 98	3:10	251 ± 23.02	0.1 ± 0.01	−29.07 ± 0.21	0.24	08	2.4
16	PTX 99	4:10	376 ± 20.41	0.1 ± 0.04	−28.61 ± 0.11	0.28	07	2.8

D: Paclitaxel, P: PLGA.