Table I.
General demographic and laboratory data in adolescent girls
| Parameter | HOMA-IR < 2.5 | HOMA-IR ≥ 2.5 | P-value |
|---|---|---|---|
| Adolescent girls, no. | 40 | 20 | |
| Age [years] | 18 (17–19) | 18 (16–19) | 0.535 |
| Weight [kg] | 64.5 (60.0–70.5) | 78.5 (68.5–96.0) | 0.002 |
| Height [cm] | 169 (166–173) | 168 (165–177) | 0.900 |
| BMI [kg/m2] | 22.6 (20.1–25.5) | 27.5 (25.2–31.5) | 0.001 |
| WC [cm] | 79.0 (73.5–87.0) | 96.0 (87.5–103.5) | < 0.001 |
| Glucose [mmol/l]* | 5.05 ±0.37 | 5.29 ±0.63 | 0.066 |
| Total proteins [g/l] | 73 (71–74) | 73 (70–74) | 0.624 |
| hsCRP [mg/l] | 0.44 (0.23–0.91) | 1.10 (0.56–2.05) | 0.002 |
| RBP4 [mg/l] | 28 (26–32) | 35 (29–41) | 0.004 |
| Fe [μmol/l] | 19.5 (13.2–25.1) | 12.6 (6.9–17.4) | 0.051 |
| Transferrin [g/l]* | 2.53 ±0.35 | 2.80 ±0.39 | 0.008 |
| sTfR [mg/dl]* | 12.08 ±2.37 | 14.60 ±3.91 | 0.003 |
| Ferritin [μg/l] | 23.8 (19.7–30.8) | 36.2 (20.0–40.9) | 0.047 |
| sTfR/ferritin index | 0.49 (0.35–0.61) | 0.37 (0.32–0.63) | 0.355 |
| sTfR/log ferritin index | 8.47 (7.35–10.32) | 9.10 (7.75–11.46) | 0.259 |
| Insulin [IU/ml] | 4.05 (3.40–6.80) | 16.15 (13.90–24.00) | < 0.001 |
| HOMA-IR | 0.90 (0.78–1.53) | 3.44 (3.09–5.95) | < 0.001 |
Data are shown as median (interquartile range). P for Mann-Whitney U test.
*
Data are presented as mean ± standard deviation.
P for Student’s t-test. BMI – body mass index, WC – waist circumference, hsCRP – high-sensitivity C-reactive protein, RBP4 – retinol-binding protein 4, sTfR – soluble transferrin receptor, HOMA-IR – homeostasis model assessment of insulin resistance.