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. 2023 Jul 25;10:1227027. doi: 10.3389/fnut.2023.1227027

Table 2.

The components and effects of Schisandra chinensis detected by MS.

Types MS methods Components Effects References
Polyphenols HPLC-ESI-MS Cya-3-O-xylrut Antioxidant (37)
GC–MS; ESI-TQMS Cyanidin 3-Rutinoside Inhibiting allergic inflammation (39)
Lignans HPLC-ESI-TOF-MS Gomisin D scavenging ABTS+ radicals (46)
SFC-DAD schisandrin Regulating the gut microbiota; Antidepressant (48)
UPLC-Q-TOF-MS schisandrol A Inhibiting pulmonary fibrosis; Improving symptoms of acute myocardial ischemia (49, 50)
UHPLC Schisandrin B Inhibiting hepatic steatosis and promoted fatty acid oxidation and improving NAFLD (58)
HPLC Schisandrol A; gomisin N promoting testosterone biosynthesis (68)
HPLC–MS/MS Schisandrin C Inhibiting the production and trypsin levels (69)
HPLC-ESI-MS Schisantherin A Improving the learning and memory abilities of chronic fatigue mice (74)
LC-MS/MS schisandrol B(gomisin A) Improving APAP-induced acute hepatotoxicity and promoting liver regeneration (77)
HR-EI-MS gomisin L1 Anti-HIV (80)
HPLC α-Iso-cubebene Inhibiting vascular inflammation with subsequent intimal hyperplasia related to vascular injury (82)
Triterpenoids HR-ESI-MS schinchinenlactone D, Propinic lactone A, Schisanbilactone A Inhibiting inflammation (92)
Organic acids HPLC; GC-MS Levulinic acid Inhibiting the excessive hyperfunction of small intestinal propulsion (102)
Polysaccharide HPLC WSP Improving the gut microbiota and antibiotic-associated diarrhea (113)
GC–MS SCPP11 Improving immune response and anti-tumor effects (115)
GPC; GC-MS polysaccharide-1 Alleviating airway inflammation in chronic cough guinea pigs to exert antitussive effects (116)
HPLC-GC-MS; FTIR SCP2-1 Improving LPS-induced cognitive dysfunction in mice and ameliorating excessive inflammatory response (117)
UPLC-Q-TOF-MS SCP2 Improving cognitive dysfunction and reversing the metabolic profile disorder in Alzheimer’s disease rats (118)
HPLC; GC-MS SCPP22 Reversing PCB126-induced immunosuppression (119)

DAD, diode array detection; EI, electron ionization; ESI, electrospray ionization; FTIR, fourier transform infrared spectroscopy; GC, gas chromatography; GPC, gel permeation chromatography; HPLC, high performance liquid chromatography; HR, high-resolution; LC, liquid chromatography; MS, mass spectrometry; NAFLD, non alcoholic fatty liver disease; Q-TOF, quadrupole time of flight; SFC, supercritical fluid chromatography; TQ, triple quadrupole; UHPLC,ultra high performance liquid chromatography; UPLC, ultra performance liquid chromatography; WSP, water-soluble polysaccharides.