Fig. 10.

Analysis by flow cytometry of HLE, KKU-M213, PANC-1 and HT-29 induced-apoptosis and necrosis following treatment with IOA-289. Cells were cultured in absence or presence of the inhibitor (3, 9 and 12 µM concentrations) for 24 h, then they were labeled with Annexin V and propidium iodide prior to analysis with the flow cytometer