Fig. 4.

Performance of the machine learning model to classify individuals as responders and non-responders based on the degree of microbiome response. a Receiver operating characteristic curves (ROC) for the final model and external validation. Confusion matrix of the training model and external validation cohorts. IBD-AID: Inflammatory bowel disease-anti-inflammatory diet; WGD: whole grain diet. b Variance importance of the top 20 features selected by the final model. Significantly different in abundance species using ordinal regression are marked with *. The importance score of each feature is indicated inside the blue circles