Table 1. Baseline Participant Characteristics (N = 10 528).
| Characteristics | Any adverse pregnancy outcome (n = 1991) | Gestational diabetes (n = 144)a | Gestational hypertension (n = 252) | Preeclampsia (n = 499) | Preterm delivery (n = 999) | Small-for-gestational-age infant (n = 526)b | No adverse pregnancy outcome (n = 8537) |
|---|---|---|---|---|---|---|---|
| Age, median (IQR), y | 57.40 (53.70-60.90) | 56.00 (53.05-59.30) | 58.60 (55.65-61.35) | 56.80 (53.10-60.70) | 57.10 (53.40-60.80) | 58.00 (54.00-61.20) | 57.20 (53.60-61.10) |
| More than 9 y of school, No. (%)c | 1764 (88.6) | 136 (94.4) | 229 (90.9) | 430 (86.2) | 894 (89.5) | 448 (85.2) | 7743 (90.7) |
| Financial strain, No./total (%)d | 164/1895 (8.7) | 19/139 (13.7) | 19/244 (7.8) | 35/473 (7.4) | 82/943 (8.7) | 52/496 (10.5) | 554/8271 (6.7) |
| Smoking status, No./total (%) | |||||||
| Never | 905/1912 (47.3) | 62/139 (44.6) | 128/240 (53.3) | 252/473 (53.3) | 478/962 (49.7) | 215/497 (43.3) | 4012/8309 (48.3) |
| Previous | 743/1912 (38.9) | 59/139 (42.4) | 87/240 (36.3) | 179/473 (37.8) | 355/962 (36.9) | 189/497 (38.0) | 3286/8309 (39.5) |
| Current | 264/1912 (13.8) | 18/139 (12.9) | 25/240 (10.4) | 42/473 (8.9) | 129/962 (13.4) | 93/497 (18.7) | 1011/8309 (12.2) |
| No. of deliveries, median (IQR)e | 2 (2-3) | 2 (2-3) | 2 (2-3) | 2 (2-3) | 2 (2-3) | 2 (2-3) | 2 (2-3) |
| Diabetes, No. (%) | 147/1988 (7.4) | 45 (31.3) | 18 (7.1) | 26/497 (5.2) | 64/997 (6.4) | 26 (4.9) | 323/8530 (3.8) |
| Previous stroke, No. (%) | 64 (3.2) | 2 (1.4) | 3 (1.2) | 22 (4.4) | 30 (3.0) | 28 (5.3) | 201 (2.4) |
| Previous myocardial infarction, No. (%) | 58 (2.9) | 2 (1.4) | 4 (1.6) | 21 (4.2) | 25 (2.5) | 24 (4.6) | 149 (1.8) |
| Previous coronary revascularization, No. (%) | 54 (2.7) | 1 (0.7) | 4 (1.6) | 20 (4.0) | 24 (2.4) | 23 (4.4) | 122 (1.4) |
| Medically treated hypertension, No./total (%) | 511/1926 (26.5) | 38/143 (26.6) | 114/250 (45.6) | 181/479 (37.8) | 203/966 (21.0) | 125/497 (25.2) | 1278/8335 (15.3) |
| Medically treated hyperlipidemia, No./total (%) | 146/1926 (7.6) | 21/143 (14.7) | 18/250 (7.2) | 36/479 (7.5) | 72/966 (7.5) | 32/497 (6.4) | 396/8335 (4.8) |
| Family history of myocardial infarction, No./total (%) | 143/1941 (7.4) | 12/143 (8.4) | 23/248 (9.3) | 31/482 (6.4) | 65/975 (6.7) | 31/506 (6.1) | 605/8406 (7.2) |
| Family history of stroke, No./total (%) | 126/1941 (6.5) | 11/143 (7.7) | 21/248 (8.5) | 35/482 (7.3) | 57/975 (5.8) | 27/506 (5.3) | 551/8406 (6.6) |
| Body mass index at age 20 y, median (IQR)f | 20.81 (19.38-22.58) [n = 1865] | 21.50 (20.05-23.09) [n = 136] | 21.36 (19.84-23.31) [n = 235] | 21.22 (19.71-22.86) [n = 470] | 20.57 (19.15-22.38) [n = 934] | 20.70 (19.23-22.06) [n = 487] | 20.75 (19.38-22.31) [n = 8110] |
| Body mass index at CCTA, median (IQR)f | 25.80 (23.10-29.30) | 27.50 (24.75-30.45) | 27.10 (24.25-30.25) | 26.50 (23.90-30.00) | 25.30 (22.70-28.70) | 25.20 (22.70-28.50) | 25.40 (23.00-28.60) |
| Systolic blood pressure, median (IQR), mm Hg | 124 (113-136) | 123 (113-135) | 132 (118-143) | 126 (116-140) | 122 (111-134) | 124 (114-135) | 120 (110-133) [n = 8535] |
| Total cholesterol, median (IQR), mg/dL | 216.2 (189.2-239.4) [n = 1987] | 202.7 (185.3-231.7) | 216.2 (196.9-239.4) [n = 251] | 216.2 (193.1-239.4) | 216.2 (189.2-239.4) [n = 997] | 216.2 (189.2-243.2) [n = 523] | 216.2 (189.2-243.2) [n = 8524] |
| High-density lipoprotein cholesterol, median (IQR), mg/dL | 69.5 (57.9-81.1) [n = 1984] | 61.8 (50.2-73.4) | 65.6 (54.1-77.2) [n = 251] | 65.6 (57.9-81.1) [n = 498] | 69.5 (57.9-81.1) [n = 995] | 69.5 (57.9-84.9) [n = 522] | 69.5 (57.9-84.9) [n = 8524] |
Abbreviation: CCTA, coronary computed tomography angiography.
SI conversions: To convert total and high-density lipoprotein cholesterol to millimoles per liter, multiply values by 0.0259.
a
Self-reported.
b
Birth weight more than 2 SDs below the mean for gestational age and sex.
c
Nine years of school is compulsory in Sweden.
d
Not able to pay an unforeseen cost of 20 000 Swedish kronor (approximately US $2000).
e
Number of deliveries per participant registered in the Swedish National Medical Birth Register.
f
Calculated as weight in kilograms divided by height in meters squared.