Table 5.
Correlates of Ebola vaccine uptake at the first offer vs. subsequent offers among vaccinated health care workers, North Kivu, Democratic Republic of the Congo, 2021 (N = 415).
| First Offer n (%) N = 292 | Multiple Offers n (%) N = 123 | OR [95% CI] | aOR [95% CI] | |
|---|---|---|---|---|
| Sex | ||||
| Male | 144 (49.3) | 54 (43.9) | Reference | Reference |
| Female | 148 (50.7) | 69 (56.1) | 0.80 [0.66–0.98] | 1.02 [0.82–1.29] |
| Age (years), median [IQR] | 36 (30–43) | 34 (27–41) | 1.24 [1.10–1.39] | 1.14 [1.02–1.29]^ |
| Highest education attained | ||||
| Primary or lower | 27 (9.3) | 12 (9.8) | Reference | Reference |
| Secondary | 119 (40.8) | 46 (37.4) | 1.15 [0.77–1.71] | 1.25 [0.79–1.98] |
| University or higher | 144 (49.3) | 65 (52.9) | 0.98 [0.69–1.40] | 0.87 [0.58–1.31] |
| Missing/declined | 2 (0.7) | 0 (0) | n/a | n/a |
| Influence of religion on vaccination | ||||
| No influence | 101 (34.6) | 39 (31.7) | Reference | Reference |
| Influences some decisions | 119 (40.8) | 44 (35.8) | 1.04 [0.74–1.48] | 1.28 [0.90–1.82] |
| Influences all decisions | 72 (24.7) | 38 (30.9) | 0.73 [0.51–1.05] | 0.78 [0.58–1.31] |
| Missing/declined | 0 (0) | 2 (1.6) | n/a | n/a |
| Ebola response team member | ||||
| No | 160 (54.8) | 81 (65.9) | Reference | Reference |
| Yes | 132 (45.2) | 42 (34.2) | 1.59 [1.24–2.04] | 1.41 [1.06–1.87] |
| Perceived risk of EVD during outbreak | ||||
| No | 16 (5.5) | 3 (2.4) | Reference | Reference |
| Yes | 276 (94.5) | 120 (97.6) | 0.43 [0.22–0.85] | 0.45 [0.22–0.89] |
| Ebola can be prevented with vaccine* | ||||
| No | 16 (5.5) | 3 (2.4) | Reference | Reference |
| Yes | 276 (94.5) | 120 (97.6) | 2.00 [1.54–2.59] | 1.92 [1.47–2.51] |
| Ebola vaccine has severe side effects* | ||||
| No | 124 (42.5) | 42 (34.2) | Reference | Reference |
| Yes | 168 (57.5) | 81 (65.8) | 0.70 [0.54–0.91] | 0.85 [0.66–1.10] |
| Mistrust of vaccine source or how it was produced* | ||||
| No | 235 (80.5) | 73 (59.4) | Reference | Reference |
| Yes | 57 (19.5) | 50 (40.7) | 0.35 [0.28–0.44] | 0.38 [0.30–0.47] |
| General vaccine confidence+ | ||||
| Low | 51 (17.5) | 38 (30.9) | Reference | Reference |
| Medium | 130 (44.5) | 57 (46.3) | 1.70 [1.28–2.26] | 1.31 [0.97–1.76] |
| High | 111 (38.0) | 28 (22.8) | 2.95 [2.11–4.13] | 2.34 [1.70–3.21] |
Only vaccinated participants who recalled the number of offers prior to acceptance were included in the 415. aOR, adjusted odds ratio from mixed-effects logistic regression model for first-offer vaccine uptake.
Recoded from a Likert scale to yes or no. ^10 years intervals. +A composite score was computed using six items, each question had a scale of 0–4 (36). Each question had a scale of 0–4 corresponding to low-high vaccine acceptance, the total composite score was then categorized as low (<25th percentile), medium (25–75th percentile), or high vaccine (>75th percentile).