Figure 5.

PR-619 suppressed tumor growth in an in vivo human chondrosarcoma xenograft. Nude mice inoculated with JJ012 and SW1353 xenografts were treated twice daily for 48 days with DMSO/saline (untreated control group, n=5) and PR-619 (10 mg/kg, i.p. n=5). A. Tumor images representing excised tumors from each group. B. Tumor volume for each group during three weeks of treatment; data are presented as means ± standard error of mean values; *P<0.05 was considered significant as compared with the control (normal saline group).