Knockdown of LRP1B promotes proliferation, accelerates cell cycle, and inhibits apoptosis in A549 cells in vitro. A, B. LRP1B mRNA expression of different cells (**P < 0.01, ***P < 0.001). C. Colony formation assays were performed to detect the proliferation of shLRP1B or shNC transfected A549 cells (***P < 0.001, **P < 0.01). D. Absorbance at 450 nm of A549 cells undergoing shLRP1B via CCK8 analysis (***P < 0.001, *P < 0.05). E. Impact of LRP1B knockdown on A549 cells cycle via cell cycle analysis (**P < 0.01). F. Detection of impact of LRP1B knockdown on A549 cells apoptosis ratio via apoptosis analysis (***P < 0.001).