Figure 3.

Expression pattern of multiple checkpoint markers among patients who received tyrosine kinase inhibitor with CSF1R inhibition (N = 21). Numbers indicate RNA expression rank, color coding was based on RNA expression rank of low, intermediate, or high, corresponding to values of 0-24, 25-74, and 75-100 percentile, respectively. Patients with intermediate or high CSF1R expression all demonstrated simultaneous intermediate or high expression of two or more other immune checkpoint proteins.