Table 2.

Popular topics of palliative and end-of-life care tweets posted in the United Kingdom before and after the start of the vaccination program.

Topics		Keywords	Examples (provided verbatim)
Before
	Topic 1: charity and fundraising	“charity,” “donation,” “fundraise,” “support,” “funding,” and “child”	Successfully made our #Covid19 #Contactfree Charity donation this evening in time for Christmas
	Topic 2: research promotion	“csilecture2020,” “hospiceuk,” “webinar,” “NHS,” “research,” “hospicecareweek,” “online,” and “bereavement”	The @cudippallmed team is planning a series of free webinars to support healthcare professionals in palliative & end of life care. Designed to inform, update & support you in issues arising during #Covid19
	Topic 3: thank and praise	“frontline,” “thank,” “work,” “support,” and “amazing”	Massive personal thank you to @TeessideHospice partners @RockliffeHall @CrathorneHall
	Topic 4: attention on care home	“visit,” “guidance,” “restriction,” “care home,” “family,” “government,” and “access”	Heartbreaking clip shows why care home visits must continue, especially at end of life # compassion #COVID19
After
	Topic 1: charity to raise funding	“charity,” “donation,” “raise,” and “support”	Amazing @StChrisHospice is still caring for people living with life-limiting illnesses despite the coronavirus. Join in a Spooktacular #Quiz to raise vital funds
	Topic 2: research promotion	“hospicecare,” “peolc hospicecare,” “bereavement,” “webinar,” “report,” “research,” and “resource”	We are regularly updating our #Coronavirus webpage. It contains links to the latest official guidance and information, and a wealth of resources, including a guide for caring for someone dying at home. #peolc #hospicecare #Covid-19
	Topic 3: thank and praise	“thank,” “proud,” “great,” “frontline,” “NHS,” “huge,” “important,” “and hospiceuk”	Very proud of our wonderful #NorthEast hospices who have done amazing work through this period, and who are supported by many of our region’s clubs
	Topic 4: attention to care home	“die,” “involve,” “address location,” “residential,” “peak,” “hospital,” “receive,” and “vaccine”	Of the 2,768 total deaths involving COVID-19, 1,802 (65.1%) occurred in hospitals, 753 (27.2%) in care homes, 13 (0.5%) in hospices and 200 (7.2%) at residential addresses or other locations