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. 2023 Jul 25;14:1214408. doi: 10.3389/fneur.2023.1214408

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Copyright © 2023 Brown, Barth, Jafri, Rumschlag, Jenkins, Atkinson and Lang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kir4.1 immunoreactivity reduction in fB^−/− mice. (A) Confocal representations of Kir4.1 staining in the cochlear lateral wall of WT and fB^−/− mice reveal diminished expression in fB^−/− mouse cochleae. Propidium iodide (PI) was used to counterstain cell nuclei. (B) A significantly reduced Kir4.1 immunoreactivity was seen in the middle and basal stria vascularis of the fB^−/− mice. Data bars represent the mean; error bars represent SEM. n = 6 and 5 cochleas for the middle turn in WT and fB^−/− group, respectively; n = 7 and 5 cochleas for the basal turn WT and fB^−/− group, respectively. Analysis was done with the Mann-Whitney U test; statistical significance was defined as a *p value of ≤ 0.05.