Skip to main content
. 2022 Sep 20;53(5):851–856. [Article in Chinese] doi: 10.12182/20220960206

表 2. Transmitted drug resistance and mutation sites in 25 HIV/AIDS patients.

25例HIV/AIDS患者传播性耐药及突变位点

Subject Genotype Protease inhibitor resistance mutations ATV/r DRV/r LPV/r NNRTI resistance mutations EFV ETR NVP RPV
 S: Susceptible; P: Potential low-level resistance; L: Low-level resistance; I: Intermediate resistance; H: High-level resistance; PI: Protease inhibitor; ATV/r: Atazanavir/ritonavir; DRV/r: Darunavir/ritonavir; LPV/r: Lopinavir/ritonavir; NNRTI: Non-nucleoside reverse transcriptase inhibitors; EFV: Efavirenz; ETR: Etravirine; NVP: Nevirapine; RPV: Rilpivirine.
1 CRF01_AE M46I P S P S S S S
2 CRF01_AE S S S G190A I P H L
3 CRF01_AE S S S V106M, Y188D H S H S
4 CRF01_AE S S S E138G, V179E L L L L
5 CRF55_01B S S S E138G, V179E L L L L
6 - S S S E138A S P S L
7 CRF01_AE S S S V179D P P P P
8 CRF01_AE S S S V179D P P P P
9 CRF01_AE S S S V179VD P P P P
10 CRF01_AE S S S V106M S P P P
11 CRF01_AE S S S V179D P P P P
12 CRF01_AE S S S V179D P P P P
13 CRF01_AE S S S V179E P P P P
14 CRF01_AE S S S V179E P P P P
15 CRF07_BC S S S V106A S P P P
16 CRF07_BC S S S V179D P P P P
17 CRF07_BC S S S V179D P P P P
18 CRF07_BC S S S V179E P P P P
19 CRF07_BC S S S V179D P P P P
20 CRF07_BC S S S V179D P P P P
21 CRF08_BC S S S V179D P P P P
22 CRF55_01B S S S V179E P P P P
23 CRF67_01B S S S V179D P P P P
24 B S S S V106A S P P P
25 S S S V179D P P P P