表 1. Results from the univariate analysis of the patient outcome in the two groups.
两组结局的单因素分析
Variable | Prognosis | P | |
Good (n=53) | Poor (n=68) | ||
CSF: Cerebrospinal fluid; EEG: Electroencephalography; IV: Intravenous; ICU: Intensive care unit. | |||
Sex/case (%) | 0.378 | ||
Male | 23 (43.4) | 35 (51.5) | |
Female | 30 (56.6) | 33 (48.5) | |
Age/yr., median (P25, P75) | 31 (21, 45) | 32 (23, 46) | 0.571 |
Disease duration/case (%) | 0.648 | ||
Acute or subacute phase (<3 months) | 47 (88.7) | 62 (91.2) | |
Chronic phase (≥3 months) | 6 (11.3) | 6 (8.8) | |
Clinical characteristics/case (%) | |||
Consciousness disorder | 30 (55.6) | 59 (86.8) | 0.000 |
Altered behavior | 33 (62.3) | 55 (80.9) | 0.023 |
Cognitive dysfunction | 42 (79.2) | 61 (89.7) | 0.109 |
Disturbance of perception | 21 (39.6) | 30 (44.1) | 0.619 |
Thought disorder | 37 (69.8) | 55 (80.9) | 0.157 |
Seizure | 26 (49.1) | 41 (60.3) | 0.217 |
Movement disorder/case (%) | 2 (3.8) | 12 (17.6) | 0.018 |
Sleep disturbance | 36 (67.9) | 43 (63.2) | 0.591 |
Emotional ability | 20 (37.7) | 35 (51.5) | 0.132 |
Autonomic dysfunction | 12 (22.6) | 8 (11.8) | 0.110 |
Prodrome symptoms | 27 (50.9) | 37 (54.4) | 0.705 |
Antibody titers/case (%) | |||
CSF | 0.063 | ||
Negative | 9 (17.0) | 3 (4.4) | |
Weakly positive | 3 (5.7) | 4 (5.9) | |
Positive | 14 (26.4) | 17 (25.0) | |
Strongly positive | 27 (50.9) | 44 (64.7) | |
Serum | 0.728 | ||
Negative | 23 (43.4) | 30 (44.1) | |
Weakly positive | 10 (18.9) | 8 (11.8) | |
Positive | 17 (32.1) | 25 (36.8) | |
Strongly positive | 3 (5.7) | 5 (7.4) | |
Auxiliary examination/case (%) | |||
MRI abnormal | 31 (58.5) | 40 (58.8) | 0.934 |
EEG abnormal | 29 (54.7) | 42 (61.8) | 0.180 |
Tumor detection | 2 (3.8) | 8 (11.8) | 0.113 |
Immunotherapy/case (%) | 0.093 | ||
No | 5 (9.4) | 1 (1.5) | |
High-dose steroids or IV immunoglobulin | 46 (86.8) | 60 (88.2) | |
High-dose steroids and IV immunoglobulin | 2 (3.8) | 4 (5.9) | |
Combined with second-line treatment | 0 (0) | 3 (4.4) | |
Transfer to ICU/case (%) | 0 (0) | 7 (10.3) | 0.016 |
Mechanical ventilation/case (%) | 1 (1.9) | 13 (19.1) | 0.003 |