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. 2022 Jan 20;53(1):142–148. [Article in Chinese] doi: 10.12182/20220160206

表 1. Results from the univariate analysis of the patient outcome in the two groups.

两组结局的单因素分析

Variable Prognosis P
Good (n=53) Poor (n=68)
 CSF: Cerebrospinal fluid; EEG: Electroencephalography; IV: Intravenous; ICU: Intensive care unit.
Sex/case (%) 0.378
 Male 23 (43.4) 35 (51.5)
 Female 30 (56.6) 33 (48.5)
Age/yr., median (P25, P75) 31 (21, 45) 32 (23, 46) 0.571
Disease duration/case (%) 0.648
 Acute or subacute phase (<3 months) 47 (88.7) 62 (91.2)
 Chronic phase (≥3 months) 6 (11.3) 6 (8.8)
Clinical characteristics/case (%)
 Consciousness disorder 30 (55.6) 59 (86.8) 0.000
 Altered behavior 33 (62.3) 55 (80.9) 0.023
 Cognitive dysfunction 42 (79.2) 61 (89.7) 0.109
 Disturbance of perception 21 (39.6) 30 (44.1) 0.619
 Thought disorder 37 (69.8) 55 (80.9) 0.157
 Seizure 26 (49.1) 41 (60.3) 0.217
Movement disorder/case (%) 2 (3.8) 12 (17.6) 0.018
 Sleep disturbance 36 (67.9) 43 (63.2) 0.591
 Emotional ability 20 (37.7) 35 (51.5) 0.132
 Autonomic dysfunction 12 (22.6) 8 (11.8) 0.110
 Prodrome symptoms 27 (50.9) 37 (54.4) 0.705
Antibody titers/case (%)
 CSF 0.063
  Negative 9 (17.0) 3 (4.4)
  Weakly positive 3 (5.7) 4 (5.9)
  Positive 14 (26.4) 17 (25.0)
  Strongly positive 27 (50.9) 44 (64.7)
 Serum 0.728
  Negative 23 (43.4) 30 (44.1)
  Weakly positive 10 (18.9) 8 (11.8)
  Positive 17 (32.1) 25 (36.8)
  Strongly positive 3 (5.7) 5 (7.4)
Auxiliary examination/case (%)
 MRI abnormal 31 (58.5) 40 (58.8) 0.934
 EEG abnormal 29 (54.7) 42 (61.8) 0.180
 Tumor detection 2 (3.8) 8 (11.8) 0.113
Immunotherapy/case (%) 0.093
 No 5 (9.4) 1 (1.5)
 High-dose steroids or IV immunoglobulin 46 (86.8) 60 (88.2)
 High-dose steroids and IV immunoglobulin 2 (3.8) 4 (5.9)
 Combined with second-line treatment 0 (0) 3 (4.4)
Transfer to ICU/case (%) 0 (0) 7 (10.3) 0.016
Mechanical ventilation/case (%) 1 (1.9) 13 (19.1) 0.003