表 3. Comparison of metabolic levels of different genotypes of ACE I/D polymorphisms subgroups .
ACE I/D多态性不同基因型亚组间代谢水平的比较
| Index | Controls | PCOS patients | |||||||
| Total (n=825) | II (n=229) | ID (n=241) | DD (n=57) | Total (n=1 020) | II (n=274) | ID (n=298) | DD (n=95) | ||
| Glu: Glucose; HDL-C: High-density lipoprotein cholesterol; HOMA-IR: Homeostatic model assessment of insulin resistance; Ins: Insulin; LDL-C: Low-density lipoprotein cholesterol; TC: Total cholesterol; TG: Triglycerides. Comparisons of all parameters were corrected for differences in age and BMI between the two subgroups, except for the parameters of age and BMI. △P <0.05, vs. the ID genotype subgroup in PCOS patients; § P<0.05, vs. the II genotype subgroup in PCOS patients. #P<0.05, vs. total controls. | |||||||||
| Fasting Ins/(pmol/L) | 62.30±35.71 | 62.18±36.81 | 63.42±35.41 | 58.05±32.72 | 105.15±71.82# | 97.35±58.32 | 110.28±75.88 | 112.05±91.48 | |
| Fasting Glu/(mmol/L) | 5.23±0.47 | 5.23±0.47 | 5.26±0.45 | 5.18±0.59 | 5.36±0.86 | 5.32±0.62 | 5.34±0.85 | 5.48±1.35 | |
| HOMA-IR | 2.21±1.29 | 2.23±1.30 | 2.24±1.31 | 2.09±1.12 | 3.78±3.06# | 3.43±2.31 | 3.93±3.18 | 4.29±4.31§ | |
| TG/(mmol/L) | 1.04±0.89 | 1.00±0.63 | 1.09±1.15 | 0.98±0.38 | 1.44±1.38# | 1.43±1.39 | 1.41±1.03 | 1.58±2.12 | |
| TC/(mmol/L) | 4.25±0.72 | 4.26±0.68 | 4.25±0.74 | 4.24±0.78 | 4.42±0.81# | 4.44±0.80 | 4.35±0.83 | 4.61±0.75△ | |
| HDL-C/(mmol/L) | 1.51±0.32 | 1.51±0.32 | 1.50±0.32 | 1.52±0.36 | 1.38±0.34# | 1.40±0.34 | 1.35±0.32 | 1.40±0.41 | |
| LDL-C/(mmol/L) | 2.36±0.63 | 2.38±0.62 | 2.35±0.64 | 2.34±0.67 | 2.56±0.76# | 2.54±0.75 | 2.54±0.77 | 2.71±0.73△ | |