表 2. List of the 20 most significant small-molecule inhibitors according to estimates of CMap analysis and mechanism of actions (MoA).
CMap和作用机制（MoA）分析预测的20种最重要的小分子抑制剂作用机理
| CMap name | Mean | Enrichment | P | MoA |
| RPS2: Ribosomal protein S2; SIRT: Sirtuin activator; TRPV: Transient receptorpotential vanilloid. | ||||
| MG-262 | −0.855 | −0.978 | 0.000 04 | |
| Prochlorperazine | −0.476 | −0.534 | 0.000 08 | Dopamine receptor antagonist |
| Withaferin A | −0.704 | −0.918 | 0.000 1 | |
| MS-275 | −0.879 | −0.989 | 0.000 3 | |
| Emetine | −0.701 | −0.89 | 0.000 3 | RPS2 |
| Metixene | −0.532 | −0.886 | 0.000 38 | Acetylcholine receptor antagonist |
| Etoposide | −0.343 | −0.885 | 0.000 38 | Topoisomerase inhibitor |
| Ciclopirox | −0.606 | −0.881 | 0.000 48 | |
| Mevalolactone | 0.562 | 0.933 | 0.000 52 | |
| Puromycin | −0.643 | −0.859 | 0.000 7 | Protein synthesis inhibitor |
| 5155877 | −0.372 | −0.85 | 0.000 93 | |
| Resveratrol | −0.537 | −0.608 | 0.000 98 | Cytochrome P450 inhibitor, SIRT activator |
| 5182598 | −0.843 | −0.976 | 0.001 27 | |
| Lomustine | −0.409 | −0.833 | 0.001 45 | |
| 5224221 | −0.839 | −0.973 | 0.001 57 | |
| Econazole | −0.382 | −0.829 | 0.001 61 | Bacterial cell wall synthesis inhibitor; Lanosterol demethylase inhibitor; Sterol demethylase inhibitor |
| Molindone | 0.37 | 0.822 | 0.001 67 | Dopamine receptor antagonist |
| Ciclosporin | −0.331 | −0.691 | 0.002 13 | |
| Thioridazine | −0.352 | −0.395 | 0.002 54 | Dopamine receptor antagonist, |
| Disulfiram | −0.446 | −0.731 | 0.002 84 | Aldehyde dehydrogenase inhibitor;
TRPV agonist; DNA methyltransferase inhibitor |