表 1. Comparison of clinical characteristics between PA group and EH group.
EH组与PA组临床资料比较
Variable | EH group (n=59) | PA group (n=125) | P |
PA: Primary aldosteronism; EH: Essential hypertension; BMI: Body mass index; CVD: Cardiovascular disease; DBP: Diastolic blood pressure; SBP: Systolic blood pressure; ARR: Aldosterone renin activity ratio; SIT: Saline infusion test; PAC: Plasma aldosterone concentration. *Median (P25, P75). 1 mmHg=0.133 kPa. | |||
Age/yr. | 48.7±12.1 | 48.1±12.1 | 0.739 |
(Male/female)/case | 25/34 | 52/73 | 0.338 |
BMI/(kg/m2) | 25.2±3.7 | 24.3±3.4 | 0.133 |
SBP/mmHg | 144±17 | 153±22 | 0.026 |
DBP/mmHg | 89±11 | 94±14 | 0.028 |
Serum Na+/(mmol·L−1) | 140.0±18.7 | 143.0±19.4 | 0.272 |
Serum K+/(mmol·L−1) | 3.70±0.36 | 3.35±0.45 | <0.001 |
Duration of hypertension*/year | 2.5 (0.3, 7.1) | 5.0 (2.0, 10.0) | 0.002 |
Diabetes mellitus or prediabetes/case (%) | 22 (37.3) | 32 (25.6) | 0.218 |
CVD/case (%) | 26 (44.5) | 45 (35.8) | 0.258 |
Upright ARR*/((ng·dL−1)/(ng·mL−1·h−1)) | 12.8 (7.2, 34.5) | 94.8 (48.4, 227.0) | <0.001 |
Post-SIT PAC*/(ng·dL−1) | 10.0 (8.3, 10.9) | 22.2 (16.1, 30.5) | <0.001 |