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. 2021 Jan 20;52(1):134–141. [Article in Chinese] doi: 10.12182/20201260301

表 3. Parameters of ROC curves of post-CCT indexes in differential diagnosis of PA and EH.

CCT后各指标对PA与EH鉴别诊断的价值

Index AUC 95%CI Optimal cut-off
value
Sensitivity/% Specificity/% Positive likelihood
ratio
Negative likelihood
ratio
 PA: Primary aldosteronism; EH: Essential hypertension; ARR: Aldosterone renin activity ratio; PAC: Plasma aldosterone concentration; PRA: Plasma renin activity; CCT: Captopril challenge test; AUC: Area under curve; CI: Confidence interval. a P<0.05, vs. post-CCT ARR; bP<0.05, vs. post-CCT PAC.
Post-CCT ARR/((ng·dL−1)/(ng·mL−1·h−1)) 0.860 0.800-0.907 32.47 84.17 72.41 3.05 0.22
Post-CCT PAC/(ng·dL−1) 0.881 0.825-0.924 19.24 78.40 88.10 6.61 0.25
Post-CCT PAC suppression rate/% 0.632a, b 0.558-0.701 33.40 95.20 32.20 1.40 0.15
Post-CCT PRA/(ng·mL−1·h−1) 0.771a, b 0.703-0.831 1.43 92.50 51.72 1.92 0.15