表 3. Parameters of ROC curves of post-CCT indexes in differential diagnosis of PA and EH.
CCT后各指标对PA与EH鉴别诊断的价值
Index | AUC | 95%CI | Optimal cut-off
value |
Sensitivity/% | Specificity/% | Positive likelihood
ratio |
Negative likelihood
ratio |
PA: Primary aldosteronism; EH: Essential hypertension; ARR: Aldosterone renin activity ratio; PAC: Plasma aldosterone concentration; PRA: Plasma renin activity; CCT: Captopril challenge test; AUC: Area under curve; CI: Confidence interval. a P<0.05, vs. post-CCT ARR; bP<0.05, vs. post-CCT PAC. | |||||||
Post-CCT ARR/((ng·dL−1)/(ng·mL−1·h−1)) | 0.860 | 0.800-0.907 | 32.47 | 84.17 | 72.41 | 3.05 | 0.22 |
Post-CCT PAC/(ng·dL−1) | 0.881 | 0.825-0.924 | 19.24 | 78.40 | 88.10 | 6.61 | 0.25 |
Post-CCT PAC suppression rate/% | 0.632a, b | 0.558-0.701 | 33.40 | 95.20 | 32.20 | 1.40 | 0.15 |
Post-CCT PRA/(ng·mL−1·h−1) | 0.771a, b | 0.703-0.831 | 1.43 | 92.50 | 51.72 | 1.92 | 0.15 |