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. 2021 Jan 20;52(1):134–141. [Article in Chinese] doi: 10.12182/20201260301

表 4. Parameters of ROC curves of post-CCT indexes in differential diagnosis of PA and LREH.

CCT后各指标对PA与LREH鉴别诊断的价值

Index AUC 95%CI Optimal cut-off
value
Sensitivity/% Specificity/% Positive likelihood
ratio
Negative likelihood
ratio
 PA: Primary aldosteronism; LREH: Low renin primary hypertension; ARR: Aldosterone renin activity ratio; PAC: Plasma aldosterone concentration; PRA: Plasma renin activity; CCT: Captopril challenge test;AUC: Area under curve; CI: Confidence interval. a P<0.05, vs. post-CCT ARR; bP<0.05, vs. post-CCT PAC.
Post-CCT ARR/((ng·dL−1)/(ng·mL−1·h−1)) 0.677 0.594-0.754 110.73 52.50 85.71 3.67 0.55
Post-CCT PAC/(ng·dL−1) 0.903a 0.843-0.946 18.17 83.20 90.48 8.74 0.19
Post-CCT PAC suppression rate/% 0.629b 0.546-0.708 33.36 95.20 33.33 1.43 0.14
Post-CCT PRA/(ng·mL−1·h−1) 0.511a, b 0.425-0.596 0.58 73.33 9.52 0.81 2.80