表 4. Parameters of ROC curves of post-CCT indexes in differential diagnosis of PA and LREH.
CCT后各指标对PA与LREH鉴别诊断的价值
Index | AUC | 95%CI | Optimal cut-off
value |
Sensitivity/% | Specificity/% | Positive likelihood
ratio |
Negative likelihood
ratio |
PA: Primary aldosteronism; LREH: Low renin primary hypertension; ARR: Aldosterone renin activity ratio; PAC: Plasma aldosterone concentration; PRA: Plasma renin activity; CCT: Captopril challenge test;AUC: Area under curve; CI: Confidence interval. a P<0.05, vs. post-CCT ARR; bP<0.05, vs. post-CCT PAC. | |||||||
Post-CCT ARR/((ng·dL−1)/(ng·mL−1·h−1)) | 0.677 | 0.594-0.754 | 110.73 | 52.50 | 85.71 | 3.67 | 0.55 |
Post-CCT PAC/(ng·dL−1) | 0.903a | 0.843-0.946 | 18.17 | 83.20 | 90.48 | 8.74 | 0.19 |
Post-CCT PAC suppression rate/% | 0.629b | 0.546-0.708 | 33.36 | 95.20 | 33.33 | 1.43 | 0.14 |
Post-CCT PRA/(ng·mL−1·h−1) | 0.511a, b | 0.425-0.596 | 0.58 | 73.33 | 9.52 | 0.81 | 2.80 |