表 5. Parameters of ROC curves of post-CCT indexes in differential diagnosis of PA and NREH.
CCT后各指标对PA与NREH鉴别诊断的价值
Index | AUC | 95%CI | Optimal cut-off
value |
Sensitivity/% | Specificity/% | Positive likelihood
ratio |
Negative likelihood
ratio |
PA: Primary aldosteronism; NREH: Normal renin primary hypertension; ARR: Aldosterone renin activity ratio; PAC: Plasma aldosterone concentration; PRA: Plasma renin activity; CCT: Captopril challenge test; AUC: Area under curve; CI: Confidence interval. a P<0.05, vs. post-CCT ARR; bP<0.05, vs. post-CCT PAC. | |||||||
Post-CCT ARR/((ng·dL−1)/(ng·mL−1·h−1)) | 0.964 | 0.921-0.987 | 22.96 | 89.17 | 91.89 | 11.00 | 0.12 |
Post-CCT PAC/(ng·dL−1) | 0.868a | 0.806-0.916 | 19.24 | 78.40 | 86.84 | 5.96 | 0.25 |
Post-CCT PAC suppression rate/% | 0.633a, b | 0.554-0.707 | 33.36 | 95.20 | 31.58 | 1.39 | 0.15 |
Post-CCT PRA/(ng·mL−1·h−1) | 0.907a | 0.850-0.947 | 0.61 | 76.67 | 91.89 | 9.46 | 0.25 |