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. 2021 Jan 20;52(1):134–141. [Article in Chinese] doi: 10.12182/20201260301

表 5. Parameters of ROC curves of post-CCT indexes in differential diagnosis of PA and NREH.

CCT后各指标对PA与NREH鉴别诊断的价值

Index AUC 95%CI Optimal cut-off
value
Sensitivity/% Specificity/% Positive likelihood
ratio
Negative likelihood
ratio
 PA: Primary aldosteronism; NREH: Normal renin primary hypertension; ARR: Aldosterone renin activity ratio; PAC: Plasma aldosterone concentration; PRA: Plasma renin activity; CCT: Captopril challenge test; AUC: Area under curve; CI: Confidence interval. a P<0.05, vs. post-CCT ARR; bP<0.05, vs. post-CCT PAC.
Post-CCT ARR/((ng·dL−1)/(ng·mL−1·h−1)) 0.964 0.921-0.987 22.96 89.17 91.89 11.00 0.12
Post-CCT PAC/(ng·dL−1) 0.868a 0.806-0.916 19.24 78.40 86.84 5.96 0.25
Post-CCT PAC suppression rate/% 0.633a, b 0.554-0.707 33.36 95.20 31.58 1.39 0.15
Post-CCT PRA/(ng·mL−1·h−1) 0.907a 0.850-0.947 0.61 76.67 91.89 9.46 0.25