表 2. Comparison of detection rates of chromosomal aberrations among different age groups.
各年龄段异常数检出率比较
Age/yr. | n | Chromosomal abnormalities/case (%) | P | Aneuploidies/case (%) | P | p/lpCNVs/case (%) | P |
p/lpCNVs: Pathogenic or likely pathogenic copy number variations. *P<0.05, vs. older than the certain age group. | |||||||
35 | 850 | 11 (1.29) | 0.079 | 3 (0.35) | 0.018* | 8 (0.94) | 0.971 |
≤36 | 1 633 | 29 (1.78) | 0.312 | 10 (0.61) | 0.013* | 19 (1.16) | 0.237 |
≤37 | 2 401 | 43 (1.79) | 0.143 | 15 (0.62) | <0.000 1* | 28 (1.17) | 0.066 |
≤38 | 2 782 | 48 (1.73) | 0.017* | 19 (0.68) | <0.000 1* | 29 (1.04) | 0.319 |
≤39 | 3 061 | 52 (1.70) | 0.001* | 22 (0.72) | <0.000 1* | 30 (0.98) | 0.695 |
≤40 | 3 288 | 57 (1.73) | <0.000 1* | 25 (0.76) | <0.000 1* | 32 (0.97) | 0.911 |