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. 2021 Jan 20;52(1):117–123. [Article in Chinese] doi: 10.12182/20210160601

表 2. Comparison of detection rates of chromosomal aberrations among different age groups.

各年龄段异常数检出率比较

Age/yr. n Chromosomal abnormalities/case (%) P Aneuploidies/case (%) P p/lpCNVs/case (%) P
 p/lpCNVs: Pathogenic or likely pathogenic copy number variations. *P<0.05, vs. older than the certain age group.
35 850 11 (1.29) 0.079 3 (0.35) 0.018* 8 (0.94) 0.971
≤36 1 633 29 (1.78) 0.312 10 (0.61) 0.013* 19 (1.16) 0.237
≤37 2 401 43 (1.79) 0.143 15 (0.62) <0.000 1* 28 (1.17) 0.066
≤38 2 782 48 (1.73) 0.017* 19 (0.68) <0.000 1* 29 (1.04) 0.319
≤39 3 061 52 (1.70) 0.001* 22 (0.72) <0.000 1* 30 (0.98) 0.695
≤40 3 288 57 (1.73) <0.000 1* 25 (0.76) <0.000 1* 32 (0.97) 0.911