图 1.

The role of NF-κB in RIHD

NF-κB在RIHD中的作用

DSBs: Double-strand breaks; ATM: Ataxia telangiectasia mutated; ROS: Reactive oxygen species; IKK: I-κB kinase; TNF-α: Tumor necrosis factor alpha; IL-1: Interleukin 1; IL-6: Interleukin 6; IL-8: Interleukin 8; VCAM-1: Vascular cell adhesion molecule-1; ICAM-1: Intercellular adhesion molecule-1; PECAM-1: Platelet endothelial cell adhesion molecule-1; NF-κB: Nuclear factor kappa-B; NOX: NADPH oxidase; COX: Cyclooxygenase; LDL: Low density lipoprotein.