表 1. Comparison of the baseline clinical data of the DFU inpatients of different renal function statuses.
不同肾功能的DFU患者的临床特征比较
Factor | Total (n=962) | Renal function (mL/[min·1.73 m2]) | P | ||
eGFR≥60 (n=696) | 15≤eGFR<60 (n=222) | eGFR<15 (n=44) | |||
eGFR: estimated glomerular filtration rate; BMI: body mass index; ABI: ankle-brachial index; CAD: coronary artery disease; PAD: peripheral artery disease; HbA1c: hemoglobin A1c; WBC: white blood cell; NEUT%: neutrocyte proportion; PCT: procalcitonin; Hb: hemoglobin; ALB: albumin. a Median (P25, P75); * P<0.05, vs. eGFR≥60 mL/(min·1.73 m2). | |||||
Male/case (%) | 602 (63) | 433 (62) | 135 (61) | 34 (77) | 0.131 |
Age/yr. | 65±12 | 64±12 | 70±11* | 65±9 | <0.001 |
Smoking/case (%) | 493 (52) | 365 (53) | 105 (48) | 23 (53) | 0.851 |
Duration of diabetes/years | 11.1±7.6 | 10.1±7.4 | 13.1±7.3* | 16.8±8.8* | <0.001 |
BMI/(kg/m2) | 23.3±3.4 | 23.3±3.5 | 23.2±2.9 | 23.9±4.0 | 0.534 |
ABI | 0.9±0.3 | 0.9±0.3 | 0.8±0.3* | 0.8±0.3 | <0.001 |
Wagner classification/case (%) | <0.001 | ||||
Grade 1 | 67 (10) | 48 (7) | 18 (8) | 1 (2) | 0.378 |
Grade 2 | 166 (17) | 123 (18) | 37 (17) | 6 (14) | 0.763 |
Grade 3 | 405 (42) | 309 (44) | 87 (39) | 9 (20%)* | 0.005 |
Grade 4 | 295 (31) | 198 (28) | 75 (34%)* | 22 (50%)* | 0.006 |
Grade 5 | 29 (3) | 18 (3) | 5 (2%)* | 6 (14%)* | <0.001 |
Hypertension/case (%) | 667 (69) | 452 (65) | 179 (81%)* | 36 (89%)* | <0.001 |
CAD/case (%) | 229 (24) | 132 (19) | 75 (34%)* | 22 (50%)* | <0.001 |
PAD/case (%) | 552 (70) | 359 (63) | 163 (86%)* | 30 (83%)* | <0.001 |
Diabetic neuropathy/case (%) | 920 (96) | 662 (96) | 215 (97) | 43 (98) | 0.718 |
HbA1c/% | 8.7±2.3 | 8.9±2.457 | 8.2±1.9* | 7.7±2.2* | <0.001 |
WBC/(×109 L-1) | 8.0±3.8 | 7.8±3.8 | 8.3±3.9 | 9.7±3.8* | 0.003 |
NEUT/% | 69±13 | 68±13 | 72±11* | 74±15* | <0.001 |
PCT/(ng/mL)a | 0.1 (0–0.1) | 0.06 (0–0.1) | 0.1 (0.06–0.13)* | 0.64 (0.23–2.06)* | <0.001 |
Hb/(g/L) | 113±22 | 117±21 | 107±21* | 94±27* | 0.008 |
ALB/(g/L) | 36±6 | 36±6 | 36±6 | 34±6 | 0.09 |