表 1. Recommendations of treatment scheme of low-dose aspirin for the prevention of preeclampsia in different guidelines.

各指南关于低剂量阿司匹林预防子痫前期用药方案推荐意见

Recommendation	ACOG (2020)[10]	NICE (2019)[11]	ISSHP (2021)[12]	FIGO (2019)[13]	China (2020)[14-15]
ACOG: the American College of Obstetricians and Gynecologists; FIGO: the International Federation of Gynecology and Obstetric; FMF: Fetal Medicine Foundation; ISSHP: International Society for the Study of Hypertension in Pregnancy; NICE: National Institutefor Health and Clinical Excellence.
Indications	Recommending aspirin if the women have any clinical high-risk factors and consider aspirin when there are more than one clinical moderate-risk factors	Advising aspirin if the women have any clinical high-risk factors or more than one clinical moderate-risk factors	Any clinical high-risk factor or more than one clinical moderate-risk factors or the FMF ‘triple test’ of multivariable screening	FMF ‘triple test’ of multivariable screening	Any clinical risk factors
Timing of starting aspirin	Between 12-18 weeks, and preferably before 16 weeks of gestation	From 12 weeks of gestation	Before 16 weeks of gestation	11-14+6 weeks of gestation	12-16 weeks of gestation
Timing of stopping aspirin	Until delivery	Until delivery	Until 36 weeks of gestation	Until 36 weeks of gestation, when delivery occurs, or when preeclampsia is diagnosed	Until 26-28 weeks of gestation
Dosage	81 mg/d	75-150 mg/d	100-162 mg/d	150 mg/d	50-150 mg/d