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. 2021 May 20;52(3):510–515. [Article in Chinese] doi: 10.12182/20210560507

表 2. Clinic manifestations of 2170 TAO patients.

2170例患者临床表现

Clinic features Extraocular muscle involvement/case (%) P
Total (n=2170) Monocular (n=541) Binocular (n=1629)
 DON:Dysthyroid optic neuropathy.
Symptoms proptosis 1199 (55.25) 259 (47.87) 940 (57.70) <0.001
Diplopia 718 (33.09) 238 (43.99) 480 (29.47) <0.001
Lid swelling 622 (28.66) 139 (25.69) 483 (29.65) 0.078
Epiphora 382 (17.60) 62 (11.46) 320 (19.64) <0.001
Eye pain 295 (13.59) 66 (12.20) 229 (14.06) 0.275
Blurring of vision 261 (12.03) 59 (10.91) 202 (12.40) 0.354
Foreign body sensation 170 (7.83) 37 (6.84) 133 (8.16) 0.320
Photophobia 120 (5.53) 16 (2.96) 104 (6.38) 0.003
Physical sign
 Lid lag 1557 (71.75) 374 (69.13) 1183 (72.62) 0.118
 Lid swelling 1461 (67.33) 293 (54.16) 1168 (71.70) <0.001
 Upper eyelid retraction 1459 (67.24) 346 (63.96) 1113 (68.32) 0.061
 lower eyelid retraction 262 (12.07) 48 (8.87) 214 (13.14) <0.001
 Lagophthalmos 364 (16.77) 55 (10.17) 309 (18.97) <0.001
 Conjunctival congestion 468 (21.57) 74 (13.68) 394 (24.19) <0.001
 Chemosis 403 (18.57) 66 (12.20) 337 (20.69) <0.001
 corneal involvement 215 (9.91) 39 (7.21) 176 (10.80) 0.015
 Proptosis 2026 (93.36) 467 (86.32) 1559 (95.70) <0.001
 Restrictive dyskinesia 1811 (83.46) 459 (84.84) 1352 (83.00) 0.316
 Strabismus 380 (17.51) 141 (26.06) 239 (14.67) <0.001
 DON 36 (1.66) 8 (1.48) 28 (1.72) 0.705
 TAO activity active 457 (21.06) 70 (12.94) 387 (23.76) <0.001