Fig. 4.

LY2828360 (10 mg/kg i.p.) increased mechanical paw withdrawal thresholds in paw ipsilateral but not contralateral to carrageenan injection in female CB2f/f and CX3CR1CRE/+; CB2f/f mice (n = 4–10 per group). LY2828360 (10 mg/kg i.p.) did not alter paw withdrawal thresholds in paw ipsilateral or contralateral to carrageenan injection in female AdvillinCRE/+; CB2f/f mice (n = 7 per group). Mean (± SEM) threshold for the ipsilateral and contralateral paw in Experiment 5, 6, 7 and 9. **p < 0.01 vs. VEH.