TABLE 2.
Top Enriched GO Terms for Molecular Functions, Biological Processes and Cellular Components
| GO term | Molecular functions | No. genes (DEG/ALL) | P value |
|---|---|---|---|
| GO:0004035 | Alkaline phosphatase activity | 3/4 | 6.40E-06 |
| GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity | 3/9 | 1.30E-04 |
| GO:0043236 | Laminin binding | 4/29 | 3.50E-04 |
| GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity | 3/19 | 1.36E-03 |
| GO:0008083 | Growth factor activity | 7/158 | 2.69E-03 |
| GO:0005178 | Integrin binding | 5/110 | 9.72E-03 |
| GO:0043394 | Proteoglycan binding | 4/38 | 1.83E-02 |
| GO:0005160 | TGFβ receptor binding | 3/48 | 1.89E-02 |
| GO:0019899 | Enzyme binding | 36/2,079 | 3.16E-02 |
| GO:0042826 | Histone deacetylase binding | 4/103 | 3.35E-02 |
| GO:0048649 | Anatomical structure formation involved in merphogenesis | 27/990 | 1.69E-03 |
| GO:0032496 | Response to lipopolysaccharide | 12/307 | 1.69E-03 |
| GO term | Biological process | No. gene (DEG/ALL) | P value |
| GO:0007565 | Female pregnancy | 11/185 | 1.20E-05 |
| GO:0001889 | Liver development | 9/20 | 2.20E-05 |
| GO:0008285 | Negative regulation of cell proliferation | 20/666 | 1.20E-04 |
| GO:0009612 | Response to mechanical stimulus | 10/206 | 1.70E-04 |
| CO:0070673 | Response to interleukin-18 | 3/10 | 1.80E-04 |
| CO:0051592 | Response to calcium ion | 7/115 | 4.20E-4 |
| CO:0030512 | Negative regulation of TGFβ receptor signaling pathway | 5/67 | 1.15E-03 |
| CO:0001936 | Regulation of endothelial cell proliferation | 6/103 | 1.36E-03 |
| CO:0048646 | Anatomical structure formation involved in morphogensis | 27/990 | 1.59E-03 |
| CO:0032496 | Response to lipopolysaccharide | 12/30 | 1.69e-03 |
| GO term | Cellular components | No. genes (DEG/ALL) | P value |
| GO:0009897 | External side of plasma membrane | 10/248 | 6.60E-04 |
| GO:0031093 | Platelet alpha granule lumen | 5/66 | 1.01E-03 |
| GO:0005911 | Cell-cell junction | 13/409 | 1.01E-03 |
| GO:0000786 | Nucleosome | 5/86 | 3.27E-03 |
| GO:0005925 | Focal adhesion | 11/382 | 5.15E-03 |
| GO:0070062 | Extracellular exosome | 44/2,665 | 8.79E-03 |
| GO:0031225 | Anchored component of membrane | 6/154 | 9.24E-03 |
| GO:0045178 | Basal part of cell | 4/46 | 1.42E-02 |
| GO:0016324 | Apical plasma membrane | 8/286 | 1.88E-02 |
| GO:0005903 | Brush border | 4/95 | 2.48E-02 |