表 2. Clinical data comparison of viable VM fetuses with or without neurodevelopmental abnormalities.
有无神经发育异常的活产VM胎儿的临床资料比较
| Factor | VM with normal neurodevelopment/case (%), n=202 | VM with abnormal neurodevelopment/case (%), n=27 |
| a: 101 cases with normal neurodevelopment and 12 cases with abnormal neurodevelopment underwent amniocentesis for fetal karyotyping or chromosome microarray analysis; b: Postnatal cranial ultrasonography was performed in 93 cases with normal neurodevelopment and 11 cases with abnormal neurodevelopment; *P<0.05, vs. VM with normal neurodevelopment; #P<0.05, degrees of VM of the two groups showed statistically significant difference. | ||
| Male fetus | 124 (61.39) | 13 (48.15) |
| Abnormal chromosomal analysis of amniocentesisa | 9 (8.91) | 1 (8.33) |
| Gestational week at delivery | ||
| <28 weeks | 1 (0.00) | 0 (0.00) |
| 28-36 weeks | 42 (20.79) | 5 (18.52) |
| ≥37 weeks | 159 (78.71) | 22 (81.48) |
| Cesarean delivery | 137 (67.82) | 19 (70.37) |
| Non-isolated VM | 73 (36.14) | 11 (40.74) |
| Postnatal cranial ultrasound suggestive of VMb | 25 (26.88) | 9 (81.82)* |
| Bilateral VM | 56 (27.72) | 9 (33.33) |
| Gestational age at initial diagnosis≥28 weeks | 97 (48.02) | 17 (62.96) |
| Progression of VM | 15 (7.43) | 6 (22.22)* |
| Degrees of VM# | ||
| Mild | 159 (78.71) | 15 (55.56) |
| Moderate | 39 (19.31) | 9 (33.33) |
| Severe | 4 (1.98) | 3 (11.11) |