Fig. 1. Scheme of supramaximal resection of GBM based on RANO resect group criteria. Maximal CE resection (blue) requires less than 1 cm3 of residual contrast-enhanced lesion. Complete CE resection means the absence of a residual contrast-enhanced lesion. It is a subset of maximal CE resection (Class 2). Supramaximal CE resection (green) requires fulfilling Class 2 criteria plus less than 5 cm3 of noncontrast-enhanced lesion.
