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Sam68 further attenuated STAT3 downstream autophagy. A, B protein expression of BCL-2, Beclin1 and ATG7 examined after silencing of Sam68 (n = 3). C mRNA expression of BCL-2, Beclin1 and Runx2 was evaluated when Sam68 silencing (n = 3), D, E LC3, P62 protein level detected when overexpression of Sam68 (n = 3). F, G LC3, P62 protein level were tested after Sam68 knockdown (n = 3). ns. not significant difference, *p < 0.05, *p < 0.01, ***p < 0.001
