Table 3.
Basal parameters of the human and mouse atrial preparations (n = 6–15)
Human right atrium | 37 °C | 23 °C | 42 °C |
---|---|---|---|
basal tension (mN) | 0.87 ± 0.25 | 0.36 ± 0.13 | 0.72 ± 0.20 |
basal time-to-peak tension (ms) | 66.2 ± 11.5 | 127 ± 19.8* | 47.1 ± 5.36 |
basal relaxation time (ms) | 145 ± 14.5 | 311 ± 26.9* | 125 ± 10.5 |
Mouse left atrium | |||
basal tension (mN) | 2.18 ± 0.30 | 0.94 ± 0.28* | 1.31 ± 0.21* |
basal time-to-peak tension (ms) | 20.4 ± 0.22 | 38.4 ± 0.82* | 18.5 ± 0.16* |
basal relaxation time (ms) | 23.1 ± 0.78 | 63.0 ± 3.04* | 19.7 ± 0.80* |
Mouse right atrium | |||
basal tension (mN) | 0.96 ± 0.13 | 0.67 ± 0.11* | 0.67 ± 0.08* |
basal time-to-peak tension (ms) | 20.4 ± 0.40 | 36.8 ± 0.64* | 21.1 ± 0.72 |
basal relaxation time (ms) | 23.1 ± 0.54 | 80.6 ± 3.57* | 22.0 ± 0.80 |
basal beating rate (bpm) | 454 ± 22.2 | 120 ± 10.4* | 534 ± 3 2.1* |
*p < 0.05 vs. 37 °C