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. 2023 Aug 8;14:4757. doi: 10.1038/s41467-023-40489-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — 211 volunteers were recruited and screened for eligibility, among which 201 participants were enrolled and randomly assigned; 200 participants received the booster dose vaccination, and 1 participant refused to receive a vaccination after randomization. Participants (98 and 97) in the two groups completed the planned visits within 90 days after vaccination. One subject discontinued the trial on day 14 after vaccination (primary safety included up to that point). Four participants discontinued the follow-up visits but provided safety records up to day 28.