Table 5.
Trade-offs (marginal rates of substitution) and marginal willingness-to-pay estimates for MMNL model
Marginal willingness-to-pay estimates | Mean | 95% CI | Interpretation | |
---|---|---|---|---|
Respondent characteristic | Attribute | |||
Respondents with low-income ≤ AU$87,999 per year | Risk of recurrence at 3 years | – 794.032 | −1745.15 to 740.70 | Respondents with lower income were, on average, willing to pay an extra AU$795 (95% CI – AU$741 to AU$1745) per year for each 1% reduction in their absolute risk of recurrence at 3 years with adjuvant immunotherapy |
Respondents with high-income ≥ AU$88,000 per year | Risk of recurrence at 3 years | – 2189.55 | – 4571.05 to 1650.90 | Respondents with higher income were, on average, willing to pay an extra AU$2190 (95% CI – AU$1651 to AU$4571) for each 1% reduction in their absolute risk of recurrence at 3 years with adjuvant immunotherapy |
Respondents with low-income ≤ AU$87,999 per year | Risk of a fatal adverse event (AE) | – 1530.73 | – 8416.53 to 1527.40 | Respondents with lower income were, on average, willing to pay AU$1531 (95% CI – AU$1527 to AU$8417) for a 1% lower chance of fatal AE |
Respondents with high-income ≥ AU$88,000 per year | Risk of a fatal AE | – 4265.71 | – 13,997.35 to 3484.34 | Respondents with higher income were, on average, willing to pay AU$4266 (95% CI – AU$3484 to AU$13,997) for a 1% lower chance of fatal AE |
Marginal rates of substitution estimates | ||||
Risk of recurrence at 3 years risk of a permanent AE | – 4.42 | – 23.41 to 10.44 | Respondents were willing to accept an additional 4% chance of a permanent AE to reduce their absolute risk of recurrence at 3 years by 1% (95% CI – 10.44 to 23.41) | |
Risk of a fatal AE risk of recurrence at 3 years | – 1.81 | – 34.54 to 12.35 | Respondents were willing to accept an additional 2% chance of recurrence at 3 years to lower their chance of a fatal AE by 1% (95% CI – 12.35 to 34.54) |