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. 2023 Jul 12;16(5):537–553. doi: 10.1007/s40271-023-00641-y

Table 3.

Estimated parameters of the multinomial logit model (discrete choice experiment, patients)

Attributes and levels Participants (n = 226)
Coeff. OR SE coeff. 95% CI p value Difference (highest to lowest level)
Type of medication 0.514
 Pill-based treatment 0.289 1.335 0.041 0.209 0.369 0.000
 Intramuscular injection (into the muscle) − 0.225 0.798 0.041 − 0.306 − 0.145 0.000
 Subcutaneous injection (into the subcutaneous fatty tissue) − 0.064 0.938 0.040 − 0.142 0.014 0.107
Frequency of dosing 1.664
 Daily − 0.906 0.404 0.065 − 1.034 − 0.778 0.000
 Weekly − 0.456 0.634 0.060 − 0.575 − 0.337 0.000
 Every 2 months 0.146 1.157 0.059 0.029 0.262 0.014
 Every 3 months 0.459 1.583 0.059 0.342 0.576 0.000
 Every 6 months 0.758 2.133 0.062 0.635 0.881 0.000
Location of treatment 0.340
 Physicians’ practice/hospital (medical staff administers treatment) − 0.170 0.844 0.017 − 0.204 − 0.136 0.000
 Home-based (self-administered treatment) 0.170 1.185 0.017 0.136 0.204 0.000
Risk of short-term side effects 0.494
 Low risk (1 of 1000 patients will experience short-term side effects) 0.207 1.230 0.040 0.128 0.286 0.000
 Moderate risk (10 of 1000 patients will experience short-term side effects) 0.080 1.083 0.040 0.001 0.159 0.046
 Higher risk (100 of 1000 patients will experience short-term side effects) − 0.287 0.751 0.041 − 0.367 − 0.207 0.000
Risk of long-term side effects 1.298
 Low risk (1 of 1000 patients will experience short-term side effects) 0.537 1.711 0.041 0.456 0.619 0.000
 Moderate risk (10 of 1000 patients will experience short-term side effects) 0.224 1.251 0.040 0.146 0.302 0.000
 Higher risk (100 of 1000 patients will experience short-term side effects) − 0.761 0.467 0.044 − 0.847 − 0.675 0.000
Interaction with other medication or (party) drugs 0.294
 No medication/drug interactions occur 0.168 1.183 0.040 0.089 0.248 0.000
 Increased risk of reduced effect due to other medication − 0.125 0.882 0.040 − 0.204 − 0.047 0.002
 Increased risk of reduced effect due to (party) drugs − 0.043 0.958 0.040 − 0.122 0.036 0.286

CI confidence interval, coeff. coefficient, OR odds ratio, SE standard error