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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Biol Psychiatry. 2023 Feb 9;94(7):591–600. doi: 10.1016/j.biopsych.2023.01.028

Figure 4.

Figure 4

CNV × major depressive disorder (MDD) PRS interactions on mood/anxiety factor scores

Intolerant = CNV risk score (CRS)>2.86; Recurrent = any of the 61 neuropsychiatric recurrent CNVs; Intolerant recurrent = any of the 61 neuropsychiatric recurrent CNVs with a CRS>2.86; Recurrent rare = any of the 57 rare neuropsychiatric recurrent CNVs i.e., excluding the high frequency 2q13 (NPHP1), 15q11.2, 15q13.3 (CHRNA7), and ZNF92 CNVs; Intolerant recurrent rare = any of the 52 rare neuropsychiatric recurrent CNVs with a CRS>2.86 (i.e., excluding the high frequency CNVs listed above and the ZMYM5, CRYL1, VPS13B, 16q23.3, 17q21.31 CNVs with a CRS>2.86)