Table 3.
Regression analysis of phenotypic data for the mammary glands from hormone-treated pigs relative to microarray expression data from 20 792 probe sets
No. of genes | %BrDU+c | %ESR1+d | %PGR+e | %TDLU1f | %TDLU2g | %TDLU3h | No. of TBsi |
---|---|---|---|---|---|---|---|
Statistically significant at FDRa < 0.01b | 1669 | 730 | 342 | 1190 | 557 | 532 | 1206 |
Abbreviations: BrDU, 5-bromo-2-deoxyuridine; ESR1, estrogen receptor-α; MG, mammary gland; PGR, progesterone receptor; TB, terminal bud; TDLU-1, terminal ductal lobular unit-1; TDLU-2, terminal ductal lobular unit-2; TDLU-3, terminal ductal lobular unit-3.
a False discovery rate.
b α ≤ .01: P < 4.464 × 10–4.
c Percentage of BrDU-positive epithelial cells in the MG (8).
d Percentage of ESR1-positive epithelial cells in the MG (Fig. 10).
e Percentage of PGR-positive epithelial cells in the MG (Fig. 11).
f Percentage of TDLU-1 structures in the MG (8).
g Percentage of TDLU-2 structures in the MG (8).
h Percentage of TDLU-3 structures in the MG (8).
i Incidence of TBs in the MG (8).