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. 2023 Jun 5;22(8):e13899. doi: 10.1111/acel.13899

TABLE 1.

Included SNPs that are significantly associated with overweight.

SNP Nearby gene Chr. EA OA EAF β SE p‐value R 2 F statistic
rs10182181 ADCY3 2 G A 0.50 0.057 0.009 2.10E‐10 0.0016 19.88
rs10853932 KCTD15 19 C T 0.69 0.067 0.011 1.30E‐09 0.0019 23.47
rs12444979* GPRC5B 16 T C 0.06 −0.079 0.013 1.80E‐09 0.0007 7.99
rs12623218 TMEM18 2 A T 0.88 0.110 0.012 5.80E‐22 0.0025 31.08
rs13130484 GNPDA2 4 T C 0.42 0.071 0.009 3.90E‐14 0.0025 30.16
rs1421085 FTO 16 C T 0.45 0.140 0.009 5.80E‐50 0.0097 119.61
rs2030323 BDNF 11 C A 0.78 0.079 0.011 1.10E‐12 0.0021 25.97
rs2206277 TFAP2B 6 T C 0.10 0.080 0.012 5.60E‐12 0.0011 13.59
rs2568958 NEGR1 1 A G 0.65 0.062 0.009 1.10E‐11 0.0017 21.41
rs2596125 HNF4G 8 T C 0.44 −0.052 0.009 5.90E‐09 0.0013 16.32
rs523288 MC4R 18 T A 0.29 0.099 0.011 1.70E‐20 0.0040 49.31
rs633715 SEC16B 1 C T 0.27 0.078 0.011 4.00E‐12 0.0024 29.17
rs8028313 MAP2K5 15 G C 0.22 −0.065 0.011 2.00E‐09 0.0015 17.74
rs9816226 ETV5 3 T A 0.85 0.070 0.012 2.00E‐09 0.0012 15.20

Abbreviations: Chr, chromosome; EA, effect allele; EAF, effect allele frequency; OA, other allele; SE, standard error; SNP, single nucleotide polymorphism.

*

Weak instrumental variable.