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. 2023 Jul 26;10:1219729. doi: 10.3389/fvets.2023.1219729

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Copyright © 2023 Liu, Deng, Li, Zhou, Wang, Zhan and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Cd exposure on microbial abundance and serum metabolite concentrations. (A) Correlation analysis between blood microbiome and metabolites. (B) Correlation analysis between gut microbiome and metabolites. In the heatmap, red indicates a positive correlation, whereas blue indicates a negative correlation. The darker color, is associated with a higher correlation. The closeness of the color to white represented a correlation closer to zero. ^***p < 0.001, ^**p < 0.01, and ^*p < 0.05. In the correlation network diagram, green represents microorganisms and orange represents metabolites. The green line indicates a negative correlation, and the orange line indicates a positive correlation.