Table 1.

The list of serum metabolites with significant changes in the CdCl₂ group compared with the control group.

Metabolites	Sub class	VIP	p-value	FC
Sphingosine↑	Amines	10.140	0.023	0.587
Phenol sulphate↑	Arylsulfates	4.053	0.013	0.329
Indoxyl sulfate↑	Arylsulfates	7.339	0.007	0.373
p-cresol sulfate↑	Arylsulfates	4.322	0.003	0.313
Indole-3-acetylglycine↑	Amino acids, peptides, and analogs	1.545	0.022	0.318
Asparaginyl-proline↑	Amino acids, peptides, and analogs	2.297	0.035	0.356
N-stearoyl cysteine↑	Amino acids, peptides, and analogs	9.669	0.015	0.384
Phenylacetylglycine↑	Amino acids, peptides, and analogs	2.188	0.008	0.410
4-guanidinobutanoic acid↑	Amino acids, peptides, and analogs	1.424	0.037	0.545
Z-leu-leu-norvalinal↑	Amino acids, peptides, and analogs	6.335	0.034	0.726
Citrulline↑	Amino acids, peptides, and analogs	2.069	0.044	0.762
Asparaginyl-methionine↑	Amino acids, peptides, and analogs	1.547	0.026	0.785
L-glutamine↓	Amino acids, peptides, and analogs	1.093	0.030	1.491
Threonylglutamic acid↓	Amino acids, peptides, and analogs	1.584	0.020	1.867
Glutamylleucylarginine↓	Amino acids, peptides, and analogs	1.793	0.041	2.269
Docosahexaenoyl ethanolamide↓	Amino acids, peptides, and analogs	4.497	0.043	2.740
13-oxo-9,11-octadecadienoic acid↓	Lineolic acids and derivatives	7.017	0.007	2.568
Corchorifatty acid↓	Lineolic acids and derivatives	1.4236	0.008	2.618
F17-hydroxylinolenic acid↓	Lineolic acids and derivatives	3.893	0.003	3.103
(±)-(E)-13-hydroxy-10-oxo-11-octadecenoic acid↓	Lineolic acids and derivatives	5.870	0.003	3.622
7-ketocholesterol↓	Cholestane steroids	15.541	0.013	4.708
Delta-tocopherol↓	Quinone and hydroquinone lipids	4.765	0.006	11.818