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. 1999 Apr;73(4):3366–3374. doi: 10.1128/jvi.73.4.3366-3374.1999

FIG. 4.

FIG. 4

Alignment of amino acids of the M2 proteins of human and avian influenza A viruses. The open boxes indicate amino acids found almost exclusively in human influenza viruses. The solid boxes indicate human-like amino acids that are present in avian viruses. Asterisks indicate avian-like amino acids that are present in human viruses. Abbreviations for avian viruses: Ck/Bres/02, A/Chicken/Brescia/19/02 (H7N7); Fpv/Dob/27, A/FPV/Dobson/27 (H7N7); Fpv/Ros/34, A/FPV/Rostock/34 (H7N1); Fpv/Wey/34, A/FPV/Weybridge (H7N7); Shear/Aus/72, A/Shearwater/Australia/1/72 (H6N5); Ck/HK/14/76, A/Chicken/Hong Kong/14/76 (H1N1); Dk/HK/193/77, A/Duck/Hong Kong/193/77 (H1N2); Budg/Hok/77, A/Budgerigar/Hokkaido/1/77 (H4N6); Dk/Bav/77, A/Duck/Bavaria/2/77 (H1N1); Mal/NY/78, A/Mallard/New York/6750/78 (H2N2); Gull/MD/78, A/Gull/Maryland/1824/78 (H13N6); Gull/MA/80, A/Gull/Massachusetts/26/80 (H13N6); Ty/MN/80, A/Turkey/Minnesota/833/80 (H4N2); Ty/MN/81, A/Turkey/Minnesota/166/81 (H1N1); Ck/PA/83, A/Chicken/Pennsylvania/1370/83 (H5N2); Ck/Vic/85, A/Chicken/Victoria/1/85 (H7N7); Oys/Ger/87, A/Oyster catcher/Germany/87 (H1N1); Dk/Nan/92, A/Duck/Nanchang/1749/92 (H11N2). Abbreviations for human viruses: wsn/33, A/WSN/33 (H1N1); PR/8/34, A/Puerto Rico/8/34 (H1N1); FM/47, A/Fort Monmouth/1/47 (H1N1); FW/50, A/Fort Warren/1/50 (H1N1); Sing/57, A/Singapore/1/57 (H2N2); Lening/57, A/Leningrad/134/57 (H2N2); Ann/60, A/Ann Arbor/6/60 (H2N2); Korea/68, A/Korea/426/68 (H2N2); Aichi/68, A/Aichi/2/68 (H3N2); USSR/70, A/USSR/90/70 (H1N1); Udorn/72, A/Udorn/72 (H3N2); PCham/73, A/Port Chalmers/1/73 (H3N2); USSR/77, A/USSR/90/77 (H1N1); Bangk/79, A/Bangkok/1/79 (H3N2); Mem/88, A/Memphis/8/88 (H3N2); Guangd/89, A/Guangdong/39/89 (H3N2).