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. 2023 May 19;3(5):100211. doi: 10.1016/j.xjidi.2023.100211

Figure 9.

Figure 9

Scatterplot of SWH and KAS FC in nonlesional rebiopsy versus keloid baseline. (a) Data shown for top 50 genes in rebiopsied nonlesional skin signature by P-value (NonLes_rebiopsy compared with Ctrl). Heatmap of TPM Z scores (percentile capped at 5th and 95th) shows that this signature is reflected across keloid groups (KE_baseline, KE_rebiopsy, and KEar) but is absent in both healthy skin groups (AbPlast and Ctrl) and baseline nonlesional skin (NonLes_baseline). Some heterogeneity of signature intensity is observed within each keloid group. Biological sex, race, and biopsy type are indicated in the figure column header. (b) Scatterplots of the fold change of all genes (in gray) in KE_baseline signature against NonLes_rebiopsy. Genes in the SWH are colored red, and genes from the KAS are colored blue on the topmost layer. Genes in green are wound-healing–specific genes not significant in any of the keloid groups. Ctrl, control; F, female; FC, fold change; KAS, keloid-associated signature; M, male; SWH, shared wound healing; TPM, transcripts per million.