Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 26;14:1219324. doi: 10.3389/fneur.2023.1219324

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Muthusamy, Sivadasan, Dixon, Sudhakar, Thomas, Danda, Wszolek, Wierenga, Dhamija and Gavrilova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

MRI of brain and cervical cord in adult-onset Alexander disease. T2W axial sections with marked atrophy and intrinsic signal changes in the upper cervical cord (A) and lower medulla (B) along with symmetric signal changes in the dentate hilum of the cerebellum [arrowhead in (B)]. T2W sagittal FLAIR imaging demonstrates signal changes and atrophy of the medulla and upper cervical cord with a “tad pole” appearance (C). T2W sagittal spine imaging (D) reveals diffuse atrophy of the cervical cord. T2W FLAIR axial (E, F) and sagittal (G) demonstrate signal changes along the wall of lateral ventricles predominantly along the frontal horns.