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. 2023 Jul 26;14:1219324. doi: 10.3389/fneur.2023.1219324

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Copyright © 2023 Muthusamy, Sivadasan, Dixon, Sudhakar, Thomas, Danda, Wszolek, Wierenga, Dhamija and Gavrilova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neuroimaging in LMNB1-related autosomal-dominant leukodystrophy (autosomal-dominant adult-onset demyelinating leukodystrophy). MRI brain T2W axial section revealing symmetric signal changes in middle cerebellar peduncles (A), medial longitudinal fasciculus (arrow in B), crus cerebri [arrowhead in (B)], posterior limb of the internal capsule (D), and confluent, extensive subcortical and deep white matter changes in high frontoparietal regions. T2W sagittal (C) and axial (F) spine images show long segment signal changes along the cervical cord with the involvement of the lateral and dorsal columns.